106670-34-2

Basic information

• Product Name: 2-[(4-METHYLBENZYL)THIO]ETHANAMINE
• Synonyms: EthanaMine,2-[[(4-Methylphenyl)Methyl]thio]-;{2-[(4-methylbenzyl)thio]ethyl}amine;2-[(4-methylbenzyl)thio]ethylamine;2-[(4-methylphenyl)methylsulfanyl]ethanamine;2-[(4-methylphenyl)methylthio]ethanamine
• CAS NO: 106670-34-2
• Molecular Formula: C₁₀H₁₅NS
• Molecular Weight: 181.3
• Mol File: 106670-34-2.mol

Chemical Properties

• Boiling Point: 289.7 °C at 760 mmHg
• Flash Point: 129 °C
• Appearance: /
• Density: 1.049 g/cm³
• Vapor Pressure: 0.00217mmHg at 25°C
• CAS DataBase Reference: 2-[(4-METHYLBENZYL)THIO]ETHANAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-METHYLBENZYL)THIO]ETHANAMINE(106670-34-2)
• EPA Substance Registry System: 2-[(4-METHYLBENZYL)THIO]ETHANAMINE(106670-34-2)

Safety Data

• Hazardous Substances Data: 106670-34-2(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-[(4-METHYLBENZYL)THIO]ETHANAMINE is used as a building block in organic synthesis for its ability to participate in various chemical reactions, such as substitution and addition. Its unique structure allows for the creation of new compounds with potential applications in different fields.
Used in Pharmaceutical Research:
In Pharmaceutical Research, 2-[(4-METHYLBENZYL)THIO]ETHANAMINE is used as a chemical intermediate for the development of new drugs. Its potential biological activity makes it a candidate for further study to understand its medicinal properties and possible therapeutic applications.
Used in Chemical Reactions:
2-[(4-METHYLBENZYL)THIO]ETHANAMINE is used as a reactant in chemical reactions to form new compounds with specific properties. Its versatility in participating in substitution and addition reactions broadens its utility in creating a range of chemical products.

InChI:InChI=1/C10H15NS/c1-9-2-4-10(5-3-9)8-12-7-6-11/h2-5H,6-8,11H2,1H3/p+1

Upstream product

• 60-23-1 Cysteamine 
• 104-82-5 4-Methylbenzyl chloride 
• 156-57-0 2-mercaptoethylamine hydrochloride 

Downstream Products

• 537678-34-5 C₂₀H₁₉NO₂S₂ 
• 537678-34-5 C₂₀H₁₉NO₂S₂ 
• 106668-72-8 N-[3-(1H-Imidazol-4-yl)-propyl]-N'-[2-(4-methyl-benzylsulfanyl)-ethyl]-guanidine; hydrochloride 

Relevant articles and documents

Enantioselective Synthesis of N,S-Acetals by an Oxidative Pummerer-Type Transformation using Phase-Transfer Catalysis

Reported is the first enantioselective oxidative Pummerer-type transformation using phase-transfer catalysis to deliver enantioenriched sulfur-bearing heterocycles. This reaction includes the direct oxidation of sulfides to a thionium intermediate, followed by an asymmetric intramolecular nucleophilic addition to form chiral cyclic N,S-acetals with moderate to high enantioselectivites. Deuterium-labelling experiments were performed to identify the stereodiscrimination step of this process. Further analysis of the reaction transition states, by means of multidimensional correlations and DFT calculations, highlight the existence of a set of weak noncovalent interactions between the catalyst and substrate that govern the enantioselectivity of the reaction.

IMIDAZOLYL ALKYL GUANIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS

New imidazolylalkyl-guanidine derivatives are described, which by virtue of their agonistic action on histamine-H 2 receptors and in part also due to their additional H 1-antagonistic receptor activity can be used in the treatment of cardiac diseases, certain forms of hypertension and diseases of arterial occlusion.These imidazolylalkyl-guanidine derivatives correspond to the general formula I: STR1

Synthesis and histamine H2-agonistic activity of ring-substituted phenyl analogues of impromidine

Analogues of the H2-agonist impromidine, characterized by a substituted phenyl ring instead of the 5-methyl-4-imidazolyl group, were prepared and tested for their H2-agonistic and H1-antagonistic activity at the guinea-pig