cas 106689-41-2, 2(1H)-Pyridinone,4-hydrazino-(9CI) | Articles data ｜lookchem

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106689-41-2

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A COMPOSITION FOR TREATING OR PREVENTING A CANCER COMPRISING PYRROLOPYRIDINE DERIVATIVES
The present invention provides a composition for treating or preventing a cancer comprising a pyrrolopyridine derivative or its salt and a pharmaceutically acceptable carrier.
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Page/Page column 15

(2010/11/25)

PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
The present invention provides novel pyrrolo[3,2-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[3,2-c]pyridine derivatives or pharmaceutically a
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Page/Page column 11

(2008/06/13)

COMPOSITIONS AND TREATMENTS FOR INHIBITING KINASE AND/OR HMG-COA REDUCTASE
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Page/Page column 64

(2008/06/13)

AUTRE VOIE D'ACCES AUX 5H-PYRIDOPYRROLOPYRIDINES ET LEUR TRANSFORMATION EN DERIVES N-5 ET N-8 SUBSTITUES
4-hydrazino-1H-pyridin-2-ones obtained starting from corresponding 2,4-dihydroxypiridines react with N-acetyl 4-piperidone.The expected hydrazones then give 6,7,8,9-tetrahydro 8-acetyl-2H,5H-pyridopyrrolopyridin-1-ones by thermal Fischer indole reaction.Aromatization of these last compounds with 10 percent palladized charchoal gives 2H,5H-pyridopyrrolopyridin-1-ones providing a new reaction pathway to this series which is more convenient that the one described in the preceding paper.Whereas the alkylation of the N-matallated species derived from 1-chloro-4-methyl-5H-pyridopyrrolopyridine by alkyl halides leads to the mixture of N-5 and N-8 alkyl derivatives, 1-chloro-5H-pyridopyrrolopyridine gives only the N-5 alkylated compound.
Hung, Nguyen Chi,Bisagni, Emile
p. 2303 - 2310
(2007/10/02)

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Chemical Properties

Storage Temp.:Inert atmosphere,Store in freezer, under -20°C
PSA: 71.17000
LogP: 0.84610

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