- Synthesis and in vitro and in silico studies of 1H- and 2H-1,2,3-triazoles as antichagasic agents
-
1,2,3-triazole heterocycles stand out in medicinal chemistry for having great structural diversity and bioactivities. In this study, two series of triazoles were synthesized. One was obtained by the 1,3-dipolar cycloaddition reaction between ethyl cyanoac
- Bello, Murilo L.,Campos, Vinicius R.,Faria, Ana F. M.,Faria, Robson X.,Ferreira, Vitor F.,Forezi, Luana da S. M.,Galv?o, Raíssa M. S.,Ji, Kathya N. K.,Petzold Pauli, Fernanda,Resende, Jackson A. L. C.,Silva, Thais B.,da Silva, Fernando de C.
-
-
- Triazole [5, 4-d] pyrimidone tricyclic compounds as well as preparation method and application thereof
-
The invention relates to triazole [5, 4-d] pyrimidone tricyclic compounds as well as a preparation method and application thereof.The triazole [5, 4-d] pyrimidone tricyclic compounds are prepared by following steps: taking different substituted anilines a
- -
-
Paragraph 0064; 0077-0081; 0082
(2021/07/09)
-
- COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES
-
Disclosed herein are compounds and compositions for modulating glycolate oxidase, useful for treating oxalate-related diseases, such as hyperoxaluria, where modulating glycolate oxidase is expected to be therapeutic to a patent in need thereof. Methods of modulating glycolate oxidase activity in a human or animal subject are also provided.
- -
-
-
- The synthesis and crystal structure of 5-(4-bromophenylamino)-2- methylsulfanylmethyl-2H-1,2,3-triazol-4-carboxylic acid ethyl ester
-
The 5-(4-bromophenylamino)-2-methylsulfanylmethyl-2H-1,2,3-triazol-4- carboxylic acid ethyl ester 6 was synthesized from p-bromoaniline. The yielded product 6 was investigated with X-ray crystallographic, NMR, MS, and IR techniques. Compound 6, C13/
- Wang, Bin,Dong, Heng-Shan
-
scheme or table
p. 95 - 98
(2009/10/17)
-
- NEW METHOD FOR STUDYING THE REACTIVITIES OF α-DIAZO IMINES. INVESTIGATION OF THE CYCLIZATION OF N-SUBSTITUTED 2-DIAZOACETAMIDINES TO 1,2,3-TRIAZOLES
-
N-Substituted diazoacetamidines were generated in the reaction of N-substituted acetamidines with benzenesulfonyl azide.It is shown that their cyclization to isomeric 1,2,3-triazole characterizes the reactivities of α-diazo imines.The synthesis of 5-amino
- Dankova, E. F.,Bakulev, V. A.,Krut'ko, D. P.
-
p. 607 - 613
(2007/10/02)
-