106842-17-5Relevant articles and documents
4-Sulfonamidoanilide tertiary carbinols: A novel series of potassium channel openers
Empfield,Mayhugh,Ohnmacht,Frank,Grant,Li
, p. 775 - 778 (2007/10/03)
Sulfonamides are viable replacements for the phenylsulfonyl and benzoyl moieties initially described for the anilide tertiary carbinol series of K(ATP) potassium channel openers. The SAR of this new series and the synthetic chemistry employed to generate its members are described.