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106927-11-1

Halofantrine HCL is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 106927-11-1 Structure

  • Basic information

    1. Product Name: Halofantrine HCL
    2. Synonyms: 3-(Dibutylamino)-1-(1,3-dichloro-6-(trifluoromethyl)phenanthren-9-yl)propan-1-ol hydrochloride;Halofantrine HCL
    3. CAS NO:106927-11-1
    4. Molecular Formula: C26H30Cl2F3NO*ClH
    5. Molecular Weight: 536.8846496
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 106927-11-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Halofantrine HCL(CAS DataBase Reference)
    10. NIST Chemistry Reference: Halofantrine HCL(106927-11-1)
    11. EPA Substance Registry System: Halofantrine HCL(106927-11-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 106927-11-1(Hazardous Substances Data)

106927-11-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 106927-11-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,6,9,2 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 106927-11:
(8*1)+(7*0)+(6*6)+(5*9)+(4*2)+(3*7)+(2*1)+(1*1)=121
121 % 10 = 1
So 106927-11-1 is a valid CAS Registry Number.

106927-11-1Upstream product

106927-11-1Downstream Products

106927-11-1Relevant articles and documents

Preparation method of halofantrine hydrochloride

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Paragraph 0083-0089, (2020/08/18)

The invention provides a preparation method of halofantrine hydrochloride. The method comprises the following steps: generating corresponding acyl chloride from 4-trifluoromethyl-2-(3, 5-dichlorophenyl) phenylacetic acid and an acylating chlorination reagent, carrying out Friedel-Crafts reaction cyclization, performing condensation with N, N-di-n-butyl-beta-aminopropionate, and finally, carrying out reduction, aromatization and salification to obtain the halofantralin hydrochloride. The method has the advantages of cheap and accessible raw materials and low cost; reaction conditions are easy to realize, the technological process and operation are safe, simple and convenient, less wastewater is generated, and environmental friendliness is achieved; and the intermediate is good in stability,the reaction activity and selectivity are high, there are fewer side reactions, and the prepared halofantrine hydrochloride is few in impurity, high in purity and high in yield.

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