cas 107027-42-9, 8-METHYL-2-PYRIDIN-4-YLQUINOLINE-4-CARBOXYLIC ACID | Articles data ｜lookchem

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107027-42-9

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Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as 'minimal' DNA-intercalating antitumor agents with in vivo solid tumor activity
A series of phenyl-substituted derivatives of the 'minimal' DNA-intercalating agent N-[2-(dimethylamino)-ethyl]-2-phenylquinoline-8-carboxamide (1) have been synthesized and evaluated for in vivo antitumor activity, in a continuing search for active compo
Atwell,Baguley,Denny
p. 396 - 401
(2007/10/02)

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Chemical Properties

Boiling Point: 479.2°C at 760 mmHg
Flash Point:243.6°C
Density: 1.294g/cm³
Vapor Pressure: 5.45E-10mmHg at 25°C
PKA: 2.14±0.10(Predicted)
PSA: 63.08000
LogP: 3.30340

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