1073354-97-8

Basic information

• Product Name: 2-AMINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER
• Synonyms: 2-AMINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER;3-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-2-aMinopyridine;2-AMinopyridin-3-ylboronic acid pinacol ester;3-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-aMine;[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridin-2-yl]amine
• CAS NO: 1073354-97-8
• Molecular Formula: C₁₁H₁₇BN₂O₂
• Molecular Weight: 220.08
• Mol File: 1073354-97-8.mol

Chemical Properties

• Appearance: /
• Density: 1.09
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-AMINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER(1073354-97-8)
• EPA Substance Registry System: 2-AMINOPYRIDINE-3-BORONIC ACID, PINACOL ESTER(1073354-97-8)

Safety Data

• Statements: 36
• Safety Statements: 26
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 1073354-97-8(Hazardous Substances Data)

Usage

Uses

2-Aminopyridine-3-boronic acid, pinacol ester

Upstream product

• 54231-33-3 3-bromo-2-nitropyridine 
• 73183-34-3 bis(pinacol)diborane 
• 13534-99-1 2-Amino-3-bromopyridine 

Downstream Products

• 1262995-21-0 2-[4-(dimethylamino)phenyl]imidazo[1,2-a]pyridine-8-boronic acid 
• 1262995-23-2 C₂₁H₂₆BN₃O₂ 

Relevant articles and documents

ARYL-BIPYRIDINE AMINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I): wherein A, X, Y, Z, Q, R1, R2, R3, R4, R5, and n are described herein.

Method for synthesizing aminopyridine borate

The invention discloses a method for synthesizing aminopyridine boronate. According to the method, after nitryl-halogenated pyridine is subjected to Suzuki coupling with metal palladium and bis(glycolato)diboron and simple filtration is performed, hydrogen is directly introduced for reduction, and the product is obtained. Through the operation of the method, the situation is avoided that in the product, the other half of bisdiboron removed during coupling and aminopyridine form a complex compound; the obtained product is high in purity and yield.

Imidazo [1,2-a] pyridine-6-boronic acid frequency ester and its derivatives preparation method

The invention discloses preparation methods for imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof. The preparation methods comprise a preparation method for imidazole[1,2-a]pyridine-6-boric acid pinacol ester, a preparation method for imidazole[1,2-a]pyridine-7-boric acid pinacol ester and a preparation method for imidazole[1,2-a]pyridine-8-boric acid pinacol ester. The imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof prepared by using the preparation methods are used in the Suzuki coupling reaction for a coupling reaction with compounds like halides and TfO-R. According to a technical scheme in the invention, the preparation methods have the advantages of high reaction yield, easy purification, suitability for production, etc.

Aminoheteroaryl benzamides as kinase inhibitors

The present invention provides a compound of Formula (I) or a salt thereof; and therapeutic uses of these compounds. The present invention further provides pharmaceutical compositions comprising these compounds, and compositions comprising these compounds with a therapeutic co-agent.