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Propanoic acid, 3-hydrazinyl-, 1,1-dimethylethyl ester, also known as tert-Butyl 3-hydrazinylpropanoate, is an organic compound with a molecular structure that features a hydrazinyl group and an ester functional group. It is characterized by its reactivity and potential applications in the pharmaceutical industry.

107349-78-0

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107349-78-0 Usage

Uses

Used in Pharmaceutical Industry:
Propanoic acid, 3-hydrazinyl-, 1,1-dimethylethyl ester is used as a reactant for the preparation of highly selective JAK2 inhibitors, such as BMS-911543, which are designed for the treatment of myeloproliferative neoplasms. Its unique molecular structure allows it to play a crucial role in the development of targeted therapies for various types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 107349-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,7,3,4 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 107349-78:
(8*1)+(7*0)+(6*7)+(5*3)+(4*4)+(3*9)+(2*7)+(1*8)=130
130 % 10 = 0
So 107349-78-0 is a valid CAS Registry Number.

107349-78-0Upstream product

107349-78-0Downstream Products

107349-78-0Relevant articles and documents

Utility of azapeptides as major histocompatibility complex class II protein ligands for T-cell activation

Hart,Beeson

, p. 3700 - 3709 (2001)

Major histocompatibility complex class II (MHC II) protein binding and antigen specific activation of CD4+ "helper" T cells are demonstrated with peptides composed of the antigenic hen egg ovalbumin 325-339 peptide (OVA) substituted with azaami

Modulators of STING (Stimulator of Interferon Genes)

-

Paragraph 0211-0212; 0241-0242, (2021/04/02)

Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

Process for production of 2-pyrazolin-5-ones

-

, (2008/06/13)

A process for production of 2-pyrazolin-5-ones having the formula (I): STR1 which comprises cyclizing hydrazone derivatives having the formula (II): STR2 in the presence of a base; wherein R1, R2, R3 and R4 each represents a specific group; compounds having the formula (I) as well as compounds having the formula (II) and a process for production thereof.

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