REGIOSPECIFIC ALKYLATION OF 9-BENZYL-1,3-DIMETHYL-6-HYDROXYPYRIMIDOPURINE-2,4,8(1H,3H,9H)-TRIONE
The sodium salt of 9-benzyl-1,3-dimethyl-6-hydroxypyrimidopurine-2,4,8(1H,3H,9H)-trione (1a) reacted with a series of alkyl halides in N,N-dimethylformamide to yield 7-carbon alkylated products (1b-1).No O-alkylated products were detected.Isolated
Solomon, Daniel M.,Conn, David J.,Wong, Shing-Chun,Kaminski, James J.
p. 2179 - 2194
(2007/10/02)
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