107811-63-2

Basic information

• Product Name: 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride
• Synonyms: Galamustine hydrochloride; G-6-M; C6-GalM; C6-GLM; C6-Galactose mustard; 6-[bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride (1:1)
• CAS NO: 107811-63-2
• Molecular Formula: C₁₀H₂₀Cl₃NO₅
• Molecular Weight: 340.6285
• Mol File: 107811-63-2.mol

Chemical Properties

• Boiling Point: 397°C at 760 mmHg
• Flash Point: 193.9°C
• Vapor Pressure: 5.98E-08mmHg at 25°C
• CAS DataBase Reference: 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride(107811-63-2)
• EPA Substance Registry System: 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride(107811-63-2)

Safety Data

• Hazardous Substances Data: 107811-63-2(Hazardous Substances Data)

Upstream product

• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 4478-43-7 (1,2:3,4-di-O-isopropylidene-6-O-(p-toluensulfonate))-D-galactopiranose 
• 103626-18-2 1,2:3,4-di-O-isopropylidene-6-bis-(2-hydroxyethyl)amino-6-deoxy-α-D-galactopyranose 
• 103626-19-3 1,2:3,4-di-O-isopropylidene-6-bis-(2-chloroethyl)amino-6-deoxy-α-D-galactopyranose 

Relevant articles and documents

6-Bis-(2-chloroethyl)amino-6-deoxy-D-galactopyranose hydrochloride: Synthesis, chemical characterization, murine P388 antitumor activity, and bone marrow toxicity

6-Bis-(2-chloroethyl)amino-6-deoxy-D-galactopyranose hydrochloride has been synthesized, characterized, and evaluated for antitumor activity and bone marrow toxicity in mice. The 1D- and 2D-NMR studies show the compound to exist as a beta-anomer chair con

Galactose-C-6 nitrogen mustard compounds and their uses

Compounds of the formula STR1 wherein X is halogen; each R independently represents H, a C1 -C4 alkyl group, a C2 -C4 alkanoyl group, a phosphate group, or a sulfate, sulfonate, or benzoate group with the proviso that no more than one sulfate, sulfonate, or benzoate group is present in said compound; and R' represents R or a carbohydrate residue derived from a carbohydrate having the formula R'OH with the proviso that R' and the R on C-2 or both R groups on C-3 and C-4 together can represent an isopropylidene group; or a pharmaceutically acceptable salt thereof, are disclosed along with methods of synthesizing and using these compounds.