- The crystal structures of (Z)-ethyl 2-(4-chlorophenyl)-3-(2,4- difluorophenyl-amino)acrylate and its analogues
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The title compound, C17H14ClF2NO 2, crystallizes in monoclinic space group P21/c with unit cell dimension of a = 16.276(3) A, b = 7.5030(15) A, c = 13.812(3) A, α = 90°, β = 111.11(3)°, γ = 90° and Z = 4. The structure of the title compound reveals a Z configuration with respect to the C=C double bond in aminoacrylate fragment. The molecule is stabilized by intramolecular N-H...F and N-H...O hydrogen bonds. In the ethyl 2-aryl-3-arylaminoacrylates, electronic properties of the substituents in the aniline motif clearly affected the attached C-N bond length, and such effect is very little relative to Z-/E-configuration with respect to the C=C double bond.
- Xiao, Zhu-Ping,Fang, Rui-Qin,Liu, Tian,Wang, Xu-Dong,Huang, Ze-Jun,Liao, Mei-Lin
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- Enamines as novel antibacterials and their structure-activity relationships
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Twenty-six enamines were synthesized to screen for the antimicrobial activity. Out of the compounds, 22 were reported for the first time. Their chemical structures including E/Z-configurations were clearly determined by 1H NMR, ESI mass spectra
- Xiao, Zhu-Ping,Fang, Rui-Qin,Li, Huan-Qiu,Xue, Jia-Yu,Zheng, Yi,Zhu, Hai-Liang
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p. 1828 - 1836
(2008/12/21)
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