Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase
Cyclic acid anhydrides possessing a lipid chain have been shown to be a new class of non-peptidic inhibitors of geranylgeranyl protein-transferase type I (GGPTase-I).
Marson, Charles M.,Rioja, Alphonso S.,Brooke, Greg,Coombes,Vigushin, David M.