cas 108030-77-9, penclomedine | Articles data ｜lookchem

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108030-77-9

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Synthesis and antitumor activity of several new analogues of penclomedine and its metabolites
Analogues of penclomedine (PEN, 3,5-dichloro-4,6-dimethoxy-2-(trichloromethyl)pyridine) and its metabolites have been synthesized and evaluated as potential antitumor agents. PEN and 4-DMPEN (3,5-dichloro-4-hydroxy-6-methoxy2-(trichloromethyl)pyridine (3a
Tiwari, Anita,Riordan, James M.,Waud, William R.,Struck, Robert F.
p. 1079 - 1085
(2007/10/03)

Compound, composition and method for treating cancer
Substantially pure 3,5-dichloro-2-nethoxy-4-hydroxy-6-(trichloromethyl)pyridine or 4-demethylpenclomedine (formula I), acid addition salts thereof, pharmaceutical compositions containing the aforesaid compound, and a method of using the compound in the treatment of cancer in a mammal are disclosed.
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(2008/06/13)

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176046-79-0
3,5-dichloro-2-methoxy-4-hydroxy-6-(trichloromethyl)-pyridine

Chemical Properties

Boiling Point: 345.3°Cat760mmHg
Flash Point:162.6°C
Density: 1.58g/cm³
Vapor Pressure: 0.000124mmHg at 25°C
Refractive Index: 1.6200 (estimate)
PSA: 31.35000
LogP: 4.23230

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