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1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1), also known as SKF 83566 Hydrobromide, is a potent and selective D1-like dopamine receptor antagonist. It specifically targets the 5-HT2 receptor, making it a valuable compound in the field of neuroscience and pharmaceutical research.

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  • 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol hydrobromide

    Cas No: 108179-91-5

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  • 108179-91-5 Structure
  • Basic information

    1. Product Name: 1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)
    2. Synonyms: 1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1);SKF83566HG;8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol:hydrobromide;1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1
    3. CAS NO:108179-91-5
    4. Molecular Formula: C17H19Br2NO
    5. Molecular Weight: 413.14686
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 108179-91-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)(108179-91-5)
    11. EPA Substance Registry System: 1H-3-Benzazepin-7-ol,8-broMo-2,3,4,5-tetrahydro-3-Methyl-5-phenyl-,hydrobroMide(1:1)(108179-91-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 108179-91-5(Hazardous Substances Data)

108179-91-5 Usage

Uses

Used in Pharmaceutical Industry:
SKF 83566 Hydrobromide is used as a research compound for studying the role of D1-like dopamine receptors and 5-HT2 receptors in various neurological and psychiatric disorders. Its high potency and selectivity make it an ideal tool for investigating the underlying mechanisms of these conditions and for the development of novel therapeutic strategies.
Used in Neuroscience Research:
In the field of neuroscience, SKF 83566 Hydrobromide is used as a selective antagonist to explore the interactions between dopamine and serotonin systems in the brain. This helps researchers understand the complex signaling pathways involved in mood regulation, cognition, and other brain functions.
Used in Drug Development:
SKF 83566 Hydrobromide is utilized in the development of new drugs targeting dopamine and serotonin receptors. Its potent and selective action on the 5-HT2 receptor makes it a valuable lead compound for the creation of medications aimed at treating conditions such as schizophrenia, depression, and anxiety.

Check Digit Verification of cas no

The CAS Registry Mumber 108179-91-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,1,7 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 108179-91:
(8*1)+(7*0)+(6*8)+(5*1)+(4*7)+(3*9)+(2*9)+(1*1)=135
135 % 10 = 5
So 108179-91-5 is a valid CAS Registry Number.

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