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5-Bromo-4-methyl-1H-indazole is a heterocyclic chemical compound characterized by a molecular formula of C8H7BrN2. It features a five-membered ring with two nitrogen atoms, and the presence of a bromine atom and a methyl group provides it with unique chemical properties. 5-Bromo-4-methyl-1H-indazole is widely recognized for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as its utility in research and development across various fields. Its reactivity necessitates careful handling by trained professionals in controlled laboratory environments, with its specific applications and properties tailored to the intended use.

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  • 1082041-34-6 Structure
  • Basic information

    1. Product Name: 5-Bromo-4-methyl-1H-indazole
    2. Synonyms: 5-Bromo-4-methyl-1H-indazole;1H-Indazole,5-broMo-4-Methyl-
    3. CAS NO:1082041-34-6
    4. Molecular Formula: C8H7BrN2
    5. Molecular Weight: 211.05858
    6. EINECS: N/A
    7. Product Categories: Building Blocks;Indazole
    8. Mol File: 1082041-34-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 344.623 °C at 760 mmHg
    3. Flash Point: 162.222 °C
    4. Appearance: /
    5. Density: 1.655 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 13.21±0.40(Predicted)
    10. CAS DataBase Reference: 5-Bromo-4-methyl-1H-indazole(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-Bromo-4-methyl-1H-indazole(1082041-34-6)
    12. EPA Substance Registry System: 5-Bromo-4-methyl-1H-indazole(1082041-34-6)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 25
    3. Safety Statements: 45
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1082041-34-6(Hazardous Substances Data)

1082041-34-6 Usage

Uses

Used in Pharmaceutical Synthesis:
5-Bromo-4-methyl-1H-indazole is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits. Its unique structure allows for the creation of molecules with specific binding affinities and activities, making it a valuable component in medicinal chemistry.
Used in Agrochemical Development:
In the agrochemical industry, 5-Bromo-4-methyl-1H-indazole is utilized as an intermediate in the production of compounds designed to protect crops and enhance agricultural yields. Its incorporation into these products can lead to the development of more effective and targeted agrochemicals.
Used in Organic Synthesis:
5-Bromo-4-methyl-1H-indazole serves as a versatile building block in organic synthesis, where it can be used to construct a variety of complex organic molecules. Its reactivity and structural features make it suitable for creating compounds with specific functions in various chemical processes.
Used in Research and Development:
5-Bromo-4-methyl-1H-indazole is employed in research and development settings to explore its potential applications and to understand its chemical behavior. It aids scientists in advancing knowledge in organic chemistry, medicinal chemistry, and related fields, potentially leading to innovative applications and discoveries.

Check Digit Verification of cas no

The CAS Registry Mumber 1082041-34-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,2,0,4 and 1 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1082041-34:
(9*1)+(8*0)+(7*8)+(6*2)+(5*0)+(4*4)+(3*1)+(2*3)+(1*4)=106
106 % 10 = 6
So 1082041-34-6 is a valid CAS Registry Number.

1082041-34-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Bromo-4-methyl-1H-indazole

1.2 Other means of identification

Product number -
Other names 5-bromo-4-methyl-1H-indazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1082041-34-6 SDS

1082041-34-6Downstream Products

1082041-34-6Relevant articles and documents

Diastereoselective Copper-Mediated Conjugate Addition of Functionalized Magnesiates for the Preparation of Bisaryl Nrf2 Activators

Glogowski, Michal P.,Matthews, Jay M.,Lawhorn, Brian G.,Minbiole, Kevin P. C.

, p. 3120 - 3137 (2021/03/01)

A two-step metal-halogen exchange and diastereoselective copper-mediated Michael addition onto a complex α,β-unsaturated system has been developed and applied toward the synthesis of bisaryl Nrf2 activators. Optimization of metal-halogen exchange using (n

METHODS OF PROMOTING BETA CELL PROLIFERATION

-

, (2018/06/30)

The present disclosure provides methods of promoting proliferation of a pancreatic cell. The methods are useful for the treatment of diabetes and other diseases characterized by impaired glucose tolerance.

OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

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Page/Page column 25, (2012/11/13)

Oxadiazole substituted indazole derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptors are disclosed.

OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

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Page/Page column 17; 44, (2011/07/07)

Oxadiazole substituted indazole derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptor are disclosed.

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