1082041-90-4

Basic information

• Product Name: 5-Bromo-4-chloro-1H-indazole
• Synonyms: 5-Bromo-4-chloro-1H-indazole
• CAS NO: 1082041-90-4
• Molecular Formula: C7H4BrClN2
• Molecular Weight: 231.47706
• Mol File: 1082041-90-4.mol

Chemical Properties

• Boiling Point: 374.7 °C at 760 mmHg
• Flash Point: 180.4 °C
• Appearance: /
• Density: 1.878 g/cm³
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 11.56±0.40(Predicted)
• CAS DataBase Reference: 5-Bromo-4-chloro-1H-indazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-4-chloro-1H-indazole(1082041-90-4)
• EPA Substance Registry System: 5-Bromo-4-chloro-1H-indazole(1082041-90-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2810 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1082041-90-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
5-Bromo-4-chloro-1H-indazole is used as a building block for the synthesis of biologically active compounds, contributing to the development of new pharmaceuticals with diverse therapeutic applications.
Used in Anti-inflammatory and Analgesic Applications:
5-Bromo-4-chloro-1H-indazole is used as an anti-inflammatory and analgesic agent, potentially providing relief from inflammation and pain due to its pharmacological properties.
Used in Drug Manufacturing:
As a precursor in the manufacture of various pharmaceutical drugs, 5-Bromo-4-chloro-1H-indazole plays a crucial role in the production of medications that address a range of health conditions.
Used in Hazardous Chemical Handling:
5-Bromo-4-chloro-1H-indazole, classified as a hazardous chemical, necessitates the implementation of proper handling and safety measures to prevent any adverse health effects on individuals who come into contact with it.

Upstream product

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• 87-60-5 3-chloro-2-methylbenzenamine 

Relevant articles and documents

4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF

The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.

PHARMACEUTICAL COMPOUNDS

The invention provides new pyrazine derivatives of formula (I), or a tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the substituents are as defined herein. The invention also provides pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

ESTROGEN RECEPTOR MODULATORS AND USES THEREOF

Described herein are compounds that are estrogen receptor modulators. Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such estrogen receptor modulators, alone and in combination with other compounds, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.