- PYRAZOLOPYRIMIDINE DERIVATIVE AS SELECTIVE TRK INHIBITOR
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The present invention discloses a compound of formula (II), a tautomer thereof or a pharmaceutically acceptable salt thereof, and relates to use thereof in preparing a medicament for treating solid tumor-related diseases.
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Paragraph 0092; 0093
(2021/08/05)
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- PYRROLOPYRIMIDINES AS CFTR POTENTIATORS
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The present invention relates to compounds of Formula I, wherein R1a, R1b, R2, R3, R4, W, Y, and Z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiator
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Paragraph 0576; 0577
(2018/06/04)
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- MODULATORS OF CFTR
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Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating CFTR mediated diseases using compounds of the present invention.
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Page/Page column 105
(2009/01/20)
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