108418-13-9 Usage
Uses
Used in Pharmaceutical Industry:
Ovothiol A is used as a therapeutic agent for its potential antioxidant and detoxifying properties. It plays a crucial role in protecting cells from oxidative stress and helps in the neutralization of harmful substances, making it a valuable compound in the development of drugs targeting various diseases.
Used in Cosmetics Industry:
In the cosmetics industry, ovothiol A is used as an ingredient for its antioxidant and skin-protective properties. It can help in the development of products that aim to reduce the signs of aging, protect the skin from environmental stressors, and maintain overall skin health.
Used in Research and Development:
Ovothiol A is also utilized in research and development for its unique chemical structure and properties. It serves as a valuable tool in studying the mechanisms of oxidative stress, detoxification processes, and the development of new therapeutic strategies for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 108418-13-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,8,4,1 and 8 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 108418-13:
(8*1)+(7*0)+(6*8)+(5*4)+(4*1)+(3*8)+(2*1)+(1*3)=109
109 % 10 = 9
So 108418-13-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H11N3O2S/c1-10-3-9-6(13)5(10)2-4(8)7(11)12/h3-4,13H,2,8H2,1H3,(H,11,12)/t4-/m0/s1
108418-13-9Relevant articles and documents
In Vitro Reconstitution of the Remaining Steps in Ovothiol A Biosynthesis: C-S Lyase and Methyltransferase Reactions
Naowarojna, Nathchar,Huang, Pei,Cai, Yujuan,Song, Heng,Wu, Lian,Cheng, Ronghai,Li, Yan,Wang, Shu,Lyu, Huijue,Zhang, Lixin,Zhou, Jiahai,Liu, Pinghua
, p. 5427 - 5430 (2018)
Ovothiols are thiolhistidine derivatives. The first step of ovothiol biosynthesis is OvoA-catalyzed oxidative coupling between histidine and cysteine. In this report, the remaining steps of ovothiol A biosynthesis were reconstituted in vitro. ETA-14770 (OvoB) was reported as a PLP-dependent sulfoxide lyase, responsible for mercaptohistidine production. OvoA was found to be a bifunctional enzyme, which mediates both oxidative C-S bond formation and methylation of mercaptohistidine to afford ovothiol A. Besides reconstituting the whole biosynthetic pathway, two unique features proposed in the literature were also examined: A potential cysteine-recycling mechanism of the C-S lyase (OvoB) and the selectivity of the ?-N methyltransferase.
Total Synthesis of Marine Mercaptohistidines: Ovothiols A, B, and C
Holler, Tod P.,Ruan, Fuqiang,Spaltenstein, Andreas,Hopkins, Paul B.
, p. 4570 - 4575 (2007/10/02)
Syntheses of ovothiols A and C in optically active form and ovothiols A and B in racemic form are reported.In all cases, synthesis of an S-protected mercaptoimidazole is followed by elaboration of an amino acid side chain.
