1088884-71-2 Usage
Uses
Used in Pharmaceutical Synthesis:
2,2-dimethylazetidine HCl is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure and properties allow it to be a valuable component in the creation of various medicinal compounds.
Used in Agrochemical Production:
In the agrochemical industry, 2,2-dimethylazetidine HCl is utilized as an intermediate, playing a crucial role in the synthesis of products designed to enhance agricultural productivity and protect crops.
Used as a Reagent in Organic Synthesis:
2,2-dimethylazetidine HCl serves as a reagent in organic synthesis, facilitating various chemical reactions due to its solubility in water and organic solvents, which is essential for a wide range of organic processes.
Used as a Building Block in Chemical Production:
2,2-dimethylazetidine HCl is used as a building block in the production of diverse chemical products, underlining its versatility and importance in the creation of a broad spectrum of chemical entities.
Used in Drug Development:
Due to its distinctive chemical structure and properties, 2,2-dimethylazetidine HCl has potential applications in the development of new drugs, making it a promising candidate for research and innovation in pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1088884-71-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,8,8,8 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1088884-71:
(9*1)+(8*0)+(7*8)+(6*8)+(5*8)+(4*8)+(3*4)+(2*7)+(1*1)=212
212 % 10 = 2
So 1088884-71-2 is a valid CAS Registry Number.
1088884-71-2Relevant articles and documents
Novel acetylcholine and carbamoylcholine analogues: Development of a functionally selective α4β2 nicotinic acetylcholine receptor agonist
Hansen, Camilla P.,Jensen, Anders A.,Christensen, Jeppe K.,Balle, Thomas,Liljefors, Tommy,Fr?lund, Bente
experimental part, p. 7380 - 7395 (2009/12/07)
A series of carbamoylcholine and acetylcholine analogues were synthesized and characterized pharmacologically at neuronal nicotinic acetylcholine receptors (nAChRs). Several of the compounds displayed low nanomolar binding affinities to the α4β2 nAChR and pronounced selectivity for this subtype over α3β4, α4β4, and α7 nAChRs. The high nAChR activity of carbamoylcholine analogue 5d was found to reside in its R-enantiomer, a characteristic most likely true for all other compounds in the series. Interestingly, the pronounced α4β2 selectivities exhibited by some of the compounds in the binding assays translated into functional selectivity. Compound 5a was a fairly potent partial α4β2 nAChR agonist with negligible activities at the α3β4 and α7 subtypes, thus being one of the few truly functionally selective α4β 2 nAChR agonists published to date. Ligand-protein docking experiments using homology models of the amino-terminal domains of α4β2 and α3β4 nAChRs identified residues Val111(β2)/Ile113(β4) , Phe119(β2)/Gln121(β4), and Thr155(α4)/Ser150(α3) as possible key determinants of the α4β2/α 3β4-selectivity displayed by the analogues.
