Palladium-Catalyzed Reactions in the Synthesis of 3- and 4-Substituted Indoles. 2. Total Synthesis of the N-Acetyl Methyl Ester of (+/-)-Claviciptic Acids
The N-acetyl methyl esters of the (+/-)-claviciptic acids 9 were synthesized in 12 steps in overall 18percent yield from commercially available 2-bromo-6-nitrotoluene.The synthesis involved, as key steps, Pd(II)-catalyzed formation of the indole and seven-membered nitrogen-containing C-ring and Pd(0)-catalyzed introduction of both C-ring side-chain precursors.
Harrington, Peter J.,Hegedus, Louis S.,Daniel, Keith F. Mc
p. 4335 - 4338
(2007/10/02)
More Articles about upstream products of 108894-43-5