- Efficient Enzymatic Preparation of Flavor Esters in Water
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A straightforward biocatalytic method for the enzymatic preparation of different flavor esters starting from primary alcohols (e.g., isoamyl, n-hexyl, geranyl, cinnamyl, 2-phenethyl, and benzyl alcohols) and naturally available ethyl esters (e.g., formate, acetate, propionate, and butyrate) was developed. The biotransformations are catalyzed by an acyltransferase from Mycobacterium smegmatis (MsAcT) and proceeded with excellent yields (80-97%) and short reaction times (30-120 min), even when high substrate concentrations (up to 0.5 M) were used. This enzymatic strategy represents an efficient alternative to the application of lipases in organic solvents and a significant improvement compared with already known methods in terms of reduced use of organic solvents, paving the way to sustainable and efficient preparation of natural flavoring agents.
- Perdomo, Igor Chiarelli,Gianolio, Stefania,Pinto, Andrea,Romano, Diego,Contente, Martina Letizia,Paradisi, Francesca,Molinari, Francesco
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p. 6517 - 6522
(2019/06/20)
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- PROCESSES FOR SYNTHESIZING ESTERS BY 1,4-ADDITION OF ALKANOIC ACIDS TO MYRCENE OR ISOPRENE
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Processes are disclosed for synthesizing esters useful in flavorings and fragrances from ?-pinene, myrcene and/or isoprene. The esters can be used in the manufacture of citral, precursors to citral and other products or precursors such as vitamins, nutritional supplements, flavorings, fragrances and other products. The process includes a 1,4-addition of an alkanoic acid to the conjugated diene of myrcene (which can be generated from ?-pinene) or the conjugated diene of isoprene to produce esters thereof.
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Page/Page column 16-17
(2008/06/13)
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- Toward a total synthesis of brassinosteroids; structure assessment of the Ireland-Claisen products of geranyl and neryl esters
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As estimated by 1H NMR analysis, thermal isomerisation of the kinetic silylenolate derived from the ester (Z)-8a proceeds with acceptable diastereo and facial selectivity, thence affording an acid having the required absolute configuration for further elaboration to brassinosteroids.
- Temmem,Uguen,De Cian,Gruber
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p. 3169 - 3173
(2007/10/03)
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- OZONOLYSIS OF ALKENES AND REACTIONS OF POLYFUNCTIONAL COMPOUNDS. XLIX. SYNTHESIS OF THE CHLORINE DERIVATIVES OF ACYLPRENOLS
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The chlorine derivatives of acylprenols with a terminal isopropenyl group were obtained by the action of sulfuryl chloride on the products from ozonolysis of 1,5,9-trimethyl-(1E,5E,9E)-cyclododecatriene.
- Odinokov, V. N.,Kukovinets, O. S.,Sakharova, N. I.,Tolstikov, G. A.
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p. 1057 - 1060
(2007/10/02)
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- Synthesis of Fatty Acid Ester by Corynebacterium sp. S-401
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Resting cells and acetone-dried cells of Corynebacterium sp.S-401 catalyzed the fatty acid ester synthesis of various alcohols and fatty acids.These reactions were carried out in phosphate buffer and/or organic solvents.In some cases synthetic reactions of esters in nonpolar solvents, such as n-hexane and benzene, gave better results compared with those obtained in phosphate buffer.
- Seo, Chull Won,Yamada, Yasuhiro,Okada, Hirosuke
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p. 405 - 410
(2007/10/02)
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