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PENTANAMIDINE, also known as Pentamidine, is an aromatic diamidine compound with antiprotozoal and antimicrobial properties. It is recognized for its effectiveness in treating Pneumocystis jiroveci pneumonia in AIDS patients and is utilized for the prevention and treatment of various protozoal infections such as leishmaniasis, trypanosomiasis, and malaria. PENTANAMIDINE functions by disrupting the growth and reproduction of protozoa, contributing to the eradication of infections. Due to its potential for severe side effects like kidney damage, pancreatitis, and irregular heartbeats, it is generally reserved for patients who have not responded to other treatments or are unable to tolerate alternative medications. PENTANAMIDINE is administered through injection or inhalation and necessitates close monitoring for adverse effects.

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  • 109-51-3 Structure
  • Basic information

    1. Product Name: PENTANAMIDINE
    2. Synonyms: pentanimidamide(SALTDATA: HCl);PentanoaMidine;ValeraMidine
    3. CAS NO:109-51-3
    4. Molecular Formula: C5H12N2
    5. Molecular Weight: 100.16
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 109-51-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 141.9°C at 760 mmHg
    3. Flash Point: 39.6°C
    4. Appearance: /
    5. Density: 0.95g/cm3
    6. Vapor Pressure: 5.72mmHg at 25°C
    7. Refractive Index: 1.467
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: PENTANAMIDINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: PENTANAMIDINE(109-51-3)
    12. EPA Substance Registry System: PENTANAMIDINE(109-51-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 109-51-3(Hazardous Substances Data)

109-51-3 Usage

Uses

Used in Pharmaceutical Industry:
PENTANAMIDINE is used as an antiprotozoal and antimicrobial agent for the treatment of Pneumocystis jiroveci pneumonia in patients with AIDS. It is effective against a range of protozoal infections, including leishmaniasis, trypanosomiasis, and malaria, by interfering with the growth and reproduction of the causative protozoa.
Used in Infectious Disease Management:
PENTANAMIDINE is used as a preventive and therapeutic agent for various protozoal infections, helping to control and eradicate these diseases in patients who have failed other treatments or cannot tolerate other medications.
Used in Patient Care:
PENTANAMIDINE is used as a medication for patients with compromised immune systems or those who are intolerant to other treatments, providing an alternative option for managing severe protozoal infections.

Check Digit Verification of cas no

The CAS Registry Mumber 109-51-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 9 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 109-51:
(5*1)+(4*0)+(3*9)+(2*5)+(1*1)=43
43 % 10 = 3
So 109-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H3,6,7)

109-51-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name pentanimidamide

1.2 Other means of identification

Product number -
Other names Pentanamidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109-51-3 SDS

109-51-3Relevant articles and documents

Dual antagonist of angiotensin II receptor and endothelin receptor

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Paragraph 0262-0267, (2021/06/02)

The invention relates to dual antagonists of an angiotensin II receptor and an endothelin receptor. Specifically, the invention provides a compound represented by a formula I and a preparation method thereof. The compound can be used for treating diseases

Pyrimidinone derivatives

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, (2008/06/13)

The invention relates to pyrimidinone derivatives and the pharmaceutically acceptable salts thereof having remarkable antagonistic action against angiotensin II receptor, and thus useful in treating cardiovascular diseases caused by angiotensin II.

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