109000-40-0Relevant articles and documents
Lewis Acid Promoted Stereoselective Carbon-Carbon Bond Formation of 3-Formyl-Δ2-isoxazolines
Kamimura, Akio,Yoshihara, Kosei,Marumo, Shinji,Yamamoto, Akinori,Nishiguchi, Takeshi,et al.
, p. 5403 - 5413 (2007/10/02)
4,5-Disubstituted 3-formyl-Δ2-isoxazolines undergo the aldol, allylation, and carbonyl ene reactions in the presence of appropriate Lewis acid to give the adducts with an effective 1,3-asymmetric induction.The stereoselectivity of the reaction
METAL-HYDRIDE REDUCTION OF ISOXAZOLINE-3-CARBOXYLATE ESTERS
Caldirola, Patrizia,De Amici, Marco,De Micheli, Carlo,Wade, Peter A.,Price, David T.,Bereznak, James F.
, p. 5267 - 5272 (2007/10/02)
The reduction of a series of isoxazoline-3-carboxylate esters with sodium borohydride gave 3-(hydroxymethyl)isoxazolines in 34-98percent yield.Reduction with DIBAH gave isoxazoline-3-carboxaldehydes in 63 and 85percent yields for the two reactions studied