1093759-69-3 Usage
Uses
Used in Pharmaceutical Research:
3-DifluoroMethylpiperidine HCl is used as a synthetic building block for the creation of various drugs and bioactive compounds, leveraging its structural features to enhance the properties and effectiveness of new pharmaceuticals.
Used in Organic Chemistry:
In the realm of organic chemistry, 3-DifluoroMethylpiperidine HCl is employed as a reagent or intermediate in the synthesis of complex organic molecules, taking advantage of its unique functional groups for various chemical reactions.
Used in Medicinal Chemistry:
3-DifluoroMethylpiperidine HCl is utilized as a component in the design and synthesis of new therapeutic agents, potentially contributing to the development of novel treatments for a range of medical conditions due to its inherent biological activity and chemical versatility.
Used in Drug Development:
As a piperidine derivative, 3-DifluoroMethylpiperidine HCl is used in the exploration of new drug candidates, with its potential biological activity making it a candidate for further investigation in the advancement of pharmaceutical formulations.
Check Digit Verification of cas no
The CAS Registry Mumber 1093759-69-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,3,7,5 and 9 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1093759-69:
(9*1)+(8*0)+(7*9)+(6*3)+(5*7)+(4*5)+(3*9)+(2*6)+(1*9)=193
193 % 10 = 3
So 1093759-69-3 is a valid CAS Registry Number.
1093759-69-3Relevant articles and documents
An approach to the synthesis of 3-substituted piperidines bearing partially fluorinated alkyl groups
Subota, Andrii I.,Ryabukhin, Sergey V.,Gorlova, Alina O.,Grygorenko, Oleksandr O.,Volochnyuk, Dmitriy M.
, p. 61 - 66 (2019/05/29)
An approach to the synthesis of 3-substituted piperidines bearing partially fluorinated alkyl groups was proposed. The method was based on the DAST-mediated nucleophilic fluorination of easily available 2-bromopyridin-3-yl alcohols and ketones affording 2-bromo-3-(1-fluoroalkyl)pyridines and 2-bromo-3-(1,1-difluoroalkyl)pyridines, respectively, followed by catalytic hydrogenation. The hydrogenation step was studied with common heterogeneous Pd-, Pt-, and Rh-based catalyst. It was found that in the case of fluoroalkyl derivatives, the pyridine core reduction was accompanied by hydrodefluorination, which became a limitation of the strategy. Nevertheless, the method worked well with 1,1-difluoroalkyl derivatives
