A combination of trimethylsilyl chloride and hydrous natural montmorillonite clay: An efficient solid acid catalyst for the azidation of benzylic and allylic alcohols with trimethylsilyl azide
We present a new procedure to convert in situ natural montmorillonite clay into a partially acidified one using a catalytic amount of trimethylsilyl chloride and trace water. We demonstrate that the acidic montmorillonite can catalyze the direct azidation
Facile Direct Coupling Reactions of MOM-protected Benzylic Alcohols Using Aluminum Chloride
MOM group is one of the most commonly used protecting groups for alcohols. This study describes novel direct functionalization of the MOM-protected benzylic alcohols. Preparation of allylic compounds from benzyl MOM ethers was successfully achieved by utilization of allyltrimethylsilane and AlCl3. In addition, direct azidation of benzyl MOM ethers using TMSN3 was successful carried out under AlCl3-mediated reaction conditions. These results demonstrate that this novel synthetic procedure is a promising approach to direct functionalization of MOM-protected alcohols including allylation and azidation.
Bui, Tien Tan,Kim, Hee-Kwon
supporting information
p. 1195 - 1198
(2021/08/03)
Direct AlCl3-catalyzed transformation of benzyl THP ethers and allyl benzyl ethers
THP and allyl groups are frequently used for the protection of alcohols. In this study, novel direct transformations of benzyl THP ethers and allyl benzyl ethers, protected forms of alcohols, are reported. TMSN3 and AlCl3 were employ
Bui, Tien Tan,Kim, Hee-Kwon
p. 388 - 397
(2020/10/15)
Indium(III) bromide catalyzed direct azidation of α-hydroxyketones using TMSN3
The direct catalytic azidation of 2-hydroxy-1,2,2-triarylethanones occurs at room temperature using 2 mol % of InBr3 as Lewis acid and TMSN3 as soluble azide source. 2-Azido-1,2,2-triarylethanones have been isolated in excellent yields. The role of aryl group and stereoelectronic factors indicate that the mechanism may involve the formation of a stable carbenium ion towards azidation.
Kumar, Anil,Sharma, Ramesh K.,Singh, Tej V.,Venugopalan, Paloth
p. 10724 - 10732
(2013/12/04)
More Articles about upstream products of 1093981-40-8