109613-97-0

Basic information

• Product Name: 3-Amino-2-bromo-4-methoxypyridine
• Synonyms: 3-Amino-2-bromo-4-methoxypyridine;2-BroMo-4-Methoxypyridin-3-aMine;2-Bromo-4-methoxy-pyridin-3-ylamine
• CAS NO: 109613-97-0
• Molecular Formula: C₆H₇BrN₂O
• Molecular Weight: 203.04
• Mol File: 109613-97-0.mol

Chemical Properties

• Boiling Point: 305.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.622±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.02±0.18(Predicted)
• CAS DataBase Reference: 3-Amino-2-bromo-4-methoxypyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-2-bromo-4-methoxypyridine(109613-97-0)
• EPA Substance Registry System: 3-Amino-2-bromo-4-methoxypyridine(109613-97-0)

Safety Data

• Hazardous Substances Data: 109613-97-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-2-bromo-4-methoxypyridine is used as a chemical intermediate for the synthesis of pharmaceutical drugs. Its pyridine ring structure, which is common in many therapeutic agents, makes it a valuable component in the development of new medications.
Used in Chemical Reactions:
3-Amino-2-bromo-4-methoxypyridine is used as a reactant in various chemical reactions, contributing to the formation of different compounds with potential applications in various industries. Its unique structure allows for versatile reactivity, making it a useful building block in the synthesis of complex molecules.

Upstream product

• 620-08-6 4-methoxypyridine 
• 31872-62-5 4-methoxy-3-nitro-pyridine 
• 33631-09-3 4-methoxypyridin-3-amine 

Downstream Products

• 1313267-55-8 ethyl (2-bromo-4-methoxypyridin-3-yl)carbamate 
• 1190318-85-4 3-iodo-7-methoxy-1H-pyrrolo[3,2-b]pyridine 
• 1313267-57-0 ethyl (4-methoxy-2-((trimethylsilyl)ethynyl)pyridin-3-yl)carbamate 
• 425380-39-8 7-methoxy-1H-pyrrolo[3,2-b]pyridine 
• 37338-80-0 3,3',4,4'-tetrahydroxy-2,2'-bipyridine-1,1'-dioxide 
• 72016-31-0 orelline 
• 109613-98-1 2-bromo-3-fluoro-4-methoxypyridine 

Relevant articles and documents

INDOLE AHR INHIBITORS AND USES THEREOF

The present invention provides compounds useful as inhibitors of AHR, compositions thereof, and methods of using the same.

TGF BETA R ANTAGONISTS

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4-Azaindole Derivatives

4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

4-AZAINDOLE DERIVATIVES

4-Azaindole derivatives which are modulators of muscarinic acetylcholine receptor (mAChR) M1 and which may be effective for the prevention or disease modifying or symptomatic treatment of cognitive deficits associated with neurological disorders such as Alzheimer-type dementia (AD) or dementia with Lewy bodies (DLB), and a pharmaceutical composition comprising a 4-azaindole derivative as an active ingredient.

[4[4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-(1H-PYRROLO-PYRIDIN-YL)-METHANONES AND SYNTHESIS THEREOF

The present invention relates herein to compounds and compositions for the treatment and amelioration of inflammatory disease. Specifically the present invention relates to compounds that having a tryptase inhibition activity and the intermediates thereof, pharmaceutical compositions comprising such compounds, and a method of treating subjects suffering from a condition disease or disorder that can be ameliorated by the administration of an inhibitor of tryptase including but not limited to for example asthma and other inflammatory diseases including age-related macular degeneration.

Syntheses of Hydroxylated Bipyridines, I. - Orellanine, the Poison of a Toadstool

Two syntheses of orellanine, -3,3',4,4'-tetrol-1,1'-dioxide (5b), are developed which comprise 10 or 11 steps, respectively.The chemical reactions of 5b with diazomethane and on UV irradiation are described.