109638-78-0

Basic information

• Product Name: (R)-1-AMINOHEXYLPHOSPHONIC ACID
• Synonyms: (R)-1-AMINOHEXYLPHOSPHONIC ACID
• CAS NO: 109638-78-0
• Molecular Formula: C6H16NO3P
• Molecular Weight: 181.169901
• Mol File: 109638-78-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-1-AMINOHEXYLPHOSPHONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-AMINOHEXYLPHOSPHONIC ACID(109638-78-0)
• EPA Substance Registry System: (R)-1-AMINOHEXYLPHOSPHONIC ACID(109638-78-0)

Safety Data

• Hazardous Substances Data: 109638-78-0(Hazardous Substances Data)

Usage

Uses

Used in Chelating Applications:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a chelating agent for its ability to form stable complexes with metal ions. This property makes it useful in various industrial processes, such as water treatment and the removal of metal contaminants.
Used in Pharmaceutical Synthesis:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential applications in treating a range of medical conditions.
Used in Agrochemical Synthesis:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a building block in the creation of novel agrochemicals, such as pesticides and herbicides. Its incorporation into these compounds can lead to improved efficacy and reduced environmental impact.
Used in Corrosion Inhibition:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a corrosion inhibitor for its ability to protect metal surfaces from degradation. This application is particularly relevant in the oil and gas industry, where corrosion-resistant materials are crucial for maintaining the integrity of pipelines and storage tanks.
Used in Neurological Disorder Treatment:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a potential treatment for certain neurological disorders due to its interactions with specific receptors and enzymes in the nervous system. Further research is needed to fully understand its therapeutic potential and optimize its use in this context.
Used in Research and Development:
(R)-1-AMINOHEXYLPHOSPHONIC ACID is used as a versatile compound in research and development settings, where its unique properties can be harnessed to explore new chemical reactions, materials, and applications across various industries.

Upstream product

• 77526-43-3 dl-(1-aminohexyl)phosphonic acid diethyl ester 
• 77526-39-7 [1-(Dimethyl-hydrazono)-hexyl]-phosphonic acid diethyl ester 
• 6281-07-8 hexanoyl-phosphonic acid diethyl ester 
• 66-25-1 hexanal 
• 143646-45-1 (1-Benzyloxycarbonylamino-hexyl)-phosphonic acid diphenyl ester 

Relevant articles and documents

ORGANOPHOSPHORUS COMPOUNDS AS POTENTIAL FUNGICIDES. PART II. AMINOALKANE-, GUANIDINOALKANE-, AND THIOUREIDOALKANE-PHOSPHONIC ACIDS: PREPARATION, SPECTROSCOPY, AND FUNGICIDAL ACTIVITY

A range of α-amino-, ω-amino-, α-guanidino-, and ω-guanidinoalkanephosphonic acids has been prepared for the purpose of studying their spectroscopic features and fungicidal activity.In addition, α-thioureido-octanephosphonic acid and thioureylene-1,1-bis(1-octanephosphonic acid) were isolated during the preparation of α-guanidino-octanephosphonic acid. 31P, 1H, and 13C nmr spectral data which were obtained for solutions of the amino- and guanidino-compounds in D2O or D2O/D2SO4, and for the thioureido compounds in DMSO-d6, are discussed together with previouslyreported data for the aminophosphonic types.FAB mass spectrometry generally gives strong pseudomolecular ions + for the zwitterionic amino- and guanidino-compounds with relatively simple fragmentations.Fungicidal activity of the α-aminophosphonic acids was found to be greater than for the ω-amino compounds, with maximum activity at a chain length of three carbon atoms when used as a seed dressing for the control of Drechslera spp.Moderately good activity was shown by the thioureido compounds against a number of fungal organisms in vitro but the guanidino-compounds exhibited low activity.Key words: Organophosphorus; fungicides; aminophosphonic acids; guanidinophosphonic acids; NMR spectroscopy; FAB mass spectroscopy.

The Synthesis of 1-Aminoalkylphosphonic Acids. A Revised Mechanism of the Reaction of Phosphorus Trichloride, Amides and Aldehydes or Ketones in Acetic Acid (Oleksyszyn Reaction)

The mechanism of the amidoalkylation of trivalent phosphorus compounds in acetic acid has been reinvestigated.Evidence is presented that 1-(acylamino)alkyl acetates 5 and not N,N'-alkylidenebisamides 2 are the intermediates in this reaction.Supporting literature analogies are discussed.This paper also describes a convenient procedure for the preparation of crude (acylamino)alkyl alkanoates 5, which are excellent amidoalkylating agents.The usefulness of these reagents is demonstrated by a simple two-step "one pot" synthesis of 1-aminoalkylphosphinic acids 1.