Highly diastereoselective synthesis of chimeras of proline and glutamate
Azomethine ylides have been generated from aromatic aldimines of α-amino acid methyl esters under treatment with LiBr/Et3N and trapped with tert-butyl acrylate yielding racemic orthogonally protected cis-5-arylpyrrolidine-2,4-dicarboxylates reg
Kudryavtsev, Konstantin V.,Tsentalovich, Mikhail Yu.,Yegorov, Anton S.,Kolychev, Eugene L.