109801-21-0

Basic information

• Product Name: 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-
• Synonyms: 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-;2-fluoro-3-hydroxy-5,5-dimethylcyclohex-2-en-1-one
• CAS NO: 109801-21-0
• Molecular Formula: C₈H₁₁FO₂
• Molecular Weight: 158.17
• Mol File: 109801-21-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-(109801-21-0)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 2-fluoro-3-hydroxy-5,5-dimethyl-(109801-21-0)

Safety Data

• Hazardous Substances Data: 109801-21-0(Hazardous Substances Data)

Upstream product

• 126-81-8 dimedone 
• 10416-78-1 5,5-dimethyl-3-((trimethylsilyl)oxy)cyclohex-2-en-1-one 

Relevant articles and documents

Selective Monofluorination of β-Diketones

Treatment of silyl enol ethers of β-diketones with 5percent F2 in N2 results in the formation of 2-fluoro 1,3-diketones.The acyclic derivatives exist as keto tautomers, while the dimedone derivative is enolic.Similarly, the silyl enol ethers of β-keto esters give rise to α-fluoro-β-keto esters.

CHEMISTRY OF ORGANO HALOGENIC MOLECULES. PART 100. COMPARATIVE BEHAVIOUR OF XENON DIFLUORIDE AND CAESIUM FLUOROXYSULPHATE IN THE FLUORINATION OF ENOL ACETATES AND KETONES

Xenon difluoride and caesium fluoroxysulphate reacted in methylene chloride or acetonitrile with various enol acetates, diketones, and ketones, yielding mainly α-fluoro ketones, the course of the reaction depending on the reagent and the structure of the organic molecule.Enol acetates from cycloalkanones were converted with caesium fluoroxysulphate to α-fluoroxycycloalkanones in high yield.Xenon difluoride and caesium fluoroxysulphate converted enol acetates of benzocycloalkanones-1 to α-fluorobenzocycloalkanones, while the reactivity of enol acetates of benzocycloalkanones-2 depended on the reagent used. 1,3-Diphenyl-propane-1,3-dione and its enol acetate were converted with XeF2 and CsSO4F to mono and difluoro substituted products, the course of the reaction being dependent on the reagent.Xenon difluoride converted 1-indanone to rearranged 2,2-difluorochromane, while caesium fluoroxysulphate reacted to 1-fluoro-2-indanone with 2-indanone.

Elemental fluorine. Part 6. Fluorination of cyclic 1,3-diketones and related compounds

Direct fluorination of cyclic 1,3-diones gives 2-mono- and 2,2-di-fluorinated products. The monofluorinated compounds crystallise in their enol forms and the difluorinated compounds form stable monohydrates whose crystal structures have been elucidated. D