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1100565-41-0

C13H12ClFN2O is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1100565-41-0 Structure

  • Basic information

    1. Product Name: C13H12ClFN2O
    2. Synonyms:
    3. CAS NO:1100565-41-0
    4. Molecular Formula:
    5. Molecular Weight: 266.702
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1100565-41-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C13H12ClFN2O(CAS DataBase Reference)
    10. NIST Chemistry Reference: C13H12ClFN2O(1100565-41-0)
    11. EPA Substance Registry System: C13H12ClFN2O(1100565-41-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1100565-41-0(Hazardous Substances Data)

1100565-41-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1100565-41-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,0,0,5,6 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1100565-41:
(9*1)+(8*1)+(7*0)+(6*0)+(5*5)+(4*6)+(3*5)+(2*4)+(1*1)=90
90 % 10 = 0
So 1100565-41-0 is a valid CAS Registry Number.

1100565-41-0Downstream Products

1100565-41-0Relevant articles and documents

Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors

Teng, Xin,Keys, Heather,Yuan, Junying,Degterev, Alexei,Cuny, Gregory D.

body text, p. 3219 - 3223 (2009/04/06)

Necroptosis is a regulated caspase-independent cell death pathway resulting in morphology reminiscent of passive non-regulated necrosis. Several diverse structure classes of necroptosis inhibitors have been reported to date, including a series of [1,2,3]thiadiazole benzylamide derivatives. However, initial evaluation of mouse liver microsome stability indicated that this series of compounds was rapidly degraded. A structure-activity relationship (SAR) study of the [1,2,3]thiadiazole benzylamide series revealed that increased mouse liver microsome stability and increased necroptosis inhibitory activity could be accomplished by replacement of the 4-cyclopropyl-[1,2,3]thiadiazole with a 5-cyano-1-methylpyrrole. In addition, the SAR and the cellular activity profiles, utilizing different cell types and necroptosis-inducing stimuli, of representative [1,2,3]thiadiazole and pyrrole derivatives were very similar suggesting that the two compound series inhibit necroptosis in the same manner.

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