cas 110143-57-2, (2S,6R)-6-[[1(s)-Ethoxycarbonyl-3-phenylpropyl]amino]-5-oxo-(2-thienyl)perhydro-1,4-thiazepine | Articles data ｜lookchem

Welcome to LookChem.com Sign In|Join Free

Article Database

Home > CAS Article list >
110143-57-2

Articles about 110143-57-2Total 1 be found

Article title
Article abstract
Author
Journal number and time
Download

Angiotensin-Converting Enzyme Inhibitors: Perhydro-1,4-thiazepin-5-one Derivatives
α-amino>-5-oxoperhydro-1,4-thiazepin-4-yl>acetic acids (monoester monoacids) and their dicarboxylic acids having the hydrophobic substituents at the 2- or 3-position of the thiazepinone ring were prepared and assayed for angiotensin-converting enzyme (ACE) inhibitory activity.The dicarboxylic acids having the pseudoequatorial amino groups at the 6-position and the pseudoequatorial hydrophobic substituents at the 2- or 3-position of the chair conformation of the thiazepinone ring had potent in vitro inhibitory activity.The monoester monoacids having the hydrophobic substituents at the 2-position suppressed pressor response to angiotensin I for a longer duration than those having the substituents at the 3-position when administered orally.The structure-activity relationship was studied by conformational energy calculations of the thiazepinone ring.
Yanagisawa, Hiroaki,Ishihara, Sadao,Ando, Akiko,Kanazaki, Takuro,Miyamoto, Shuichi,et al.
p. 1984 - 1991
(2007/10/02)

More Articles about upstream products of 110143-57-2

More Articles about downstream products of 110143-57-2

Chemical Properties

Boiling Point: 644.4 °C at 760 mmHg
Flash Point:343.5 °C
Density: 1.26 g/cm³
Storage Temp.:2-8°C
Vapor Pressure: 1.7E-16mmHg at 25°C
Refractive Index: 1.614
PKA: 14.58±0.60(Predicted)
PSA: 120.97000
LogP: 3.89460

Show more

Global suppliers and manufacturers of 110143-57-2total 15 suppliers on LookChem

Company Name
Business Type
Min Order
FOB Price
Main Products
Contact

Dayang Chem (Hangzhou) Co.,Ltd.
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:USD $ 3.0-3.0 / Kilogram
Main Products:994
Country:

Henan Wentao Chemical Product Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:44
Country:

Afine Chemicals Limited
Business Type:Lab/Research institutions
Min Order:1 Kilogram
FOB Price:No Data
Main Products:95
Country:

Hangzhou J&H Chemical Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:46
Country:

Antimex Chemical Limied
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:163
Country:

Hangzhou Fandachem Co.,Ltd
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:52
Country:

Jilin haofei import and export trade Co.,Ltd
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Chemical Technology Co.,LTD
Business Type:Other
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

AOPHARM
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Shanghai Run-Biotech Co., Ltd.
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

ENAO Chemical Co, Limited
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Jiaxing Isen Chemical Co.,Ltd
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Skyrun Industrial Co.,Ltd
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.
Business Type:Lab/Research institutions
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

NovaChemistry
Business Type:Trading Company
Min Order:No Data
FOB Price:No Data
Main Products:1
Country:

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 110143-57-2

About us - Payment - Contact us - Links - Help Center - Disclaimer
SiteMap | Manufacturers | VIP Product | Suppliers | CAS | New CAS | Cas Database | Article Data | Chemical Catalog | Product Name

©2008 LookChem.com,License:ICP NO.:Zhejiang16009103 complaints:service@lookchem.com
[Hangzhou]86-571-87562588,87562561,87562573 Our Legal adviser: Lawyer