SOLUBLE FORMS OF INCLUSION COMPLEXES OF HISTONE DEACETYLASE INHIBITORS AND CYCLODEXTRINS, THEIR PREPARATION PROCESSES AND USES IN THE PHARMACEUTICAL FIELD
The invention relates to the preparation of soluble forms of complexes of histone deacetylase inhibitors and cyclodextrins. The preparation process involves the formation of inclusion complexes with cyclodextrins with the aid of microwaves. Their use is in the pharmaceutical field.
Two novel luminescent rhenium(I) diimine indole complexes have been designed and their properties studied; these conjugates can be recognised by indole-binding proteins including bovine serum albumin, lysozyme and tryptophanase.
Lo, Kenneth Kam-Wing,Tsang, Keith Hing-Kit,Hui, Wai-Ki,Zhu, Nianyong
p. 2704 - 2705
(2007/10/03)
Composition containing a penem or carbapenem antibiotic and the use of the same
Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially.
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(2008/06/13)
ANTIFIBRINOLYTIC ACTIVITY OF NICOTINIC ACID CONJUGATES WITH 6-AMINOHEXANOIC, p-AMINOMETHYLBENZOIC, AND trans-4-AMINOMETHYLCYCLOHEXANECARBOXYLIC ACIDS
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Zabelin, N. N.,Moiseenok, A. G.,Bulanova, L. N.,Kopelevich, V. M.,Gunar, V. I.
p. 334 - 338
(2007/10/02)
Composition containing a penem or carbapenem antibiotic
Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.
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(2008/06/13)
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