110590-65-3

Basic information

• Product Name: H-TYR-ILE-GLY-SER-ARG-NH2
• Synonyms: TYR-ILE-GLY-SER-ARG-NH2;TYR-ILE-GLY-SER-ARG-NH2 2ACOH 2H2O;YIGSR-NH2;H-TYR-ILE-GLY-SER-ARG-NH2;LAMININ PENTAPEPTIDE, AMIDE;LAMININ PENTAPEPTIDE YIGSR-NH2;LAMININ PENTAPEPTIDE YIGSR-NH2 2ACOH 2H2O;YIGSR aMide
• CAS NO: 110590-65-3
• Molecular Formula: C26H43N9O7
• Molecular Weight: 593.68
• Product Categories: peptide
• Mol File: 110590-65-3.mol

Chemical Properties

• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 9.97±0.15(Predicted)
• CAS DataBase Reference: H-TYR-ILE-GLY-SER-ARG-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: H-TYR-ILE-GLY-SER-ARG-NH2(110590-65-3)
• EPA Substance Registry System: H-TYR-ILE-GLY-SER-ARG-NH2(110590-65-3)

Safety Data

• Hazardous Substances Data: 110590-65-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
H-TYR-ILE-GLY-SER-ARG-NH2 is used as a research tool for studying protein-protein interactions and designing therapeutic compounds targeting specific receptors or enzymes. Its potential to interact with biological systems makes it valuable in the development of new drugs and therapies.
Used in Biomedical Research:
In the field of biomedical research, H-TYR-ILE-GLY-SER-ARG-NH2 is utilized as a compound for investigating the mechanisms of action and potential applications in medicine. Its ability to engage with biological systems allows researchers to explore its effects on various physiological processes and diseases.
Used in Drug Design:
H-TYR-ILE-GLY-SER-ARG-NH2 is employed as a building block in the design of peptide-based drugs, leveraging its interactions with biological targets to develop novel therapeutic agents. Its sequence and structure can be modified to enhance specificity, potency, and pharmacokinetic properties, contributing to the advancement of peptide drug discovery.
Used in Diagnostics:
This peptide may also be used in the development of diagnostic tools, such as assays or imaging agents, that rely on its ability to bind to specific biological targets. By targeting unique molecular interactions, H-TYR-ILE-GLY-SER-ARG-NH2 can contribute to the early detection and monitoring of diseases.
Overall, H-TYR-ILE-GLY-SER-ARG-NH2 represents a versatile compound with a range of potential applications in the pharmaceutical, biomedical, and diagnostic industries, driven by its ability to interact with biological systems and its potential for modification and optimization in drug development.

Upstream product

• 158011-31-5 Boc-Arg(N^GNO₂)-NH₂ 

Relevant articles and documents

Fmoc-amino acid chlorides-KOBt in solid phase peptide synthesis

Fmoc-amino acid chlorides can be used along with KOBt instead of the routinely employed 1:1 mixture of base (TEA or DIEA) and catalyst (HOBt or Piv) in solid phase peptide synthesis.No additional base is required.Coupling is fast and racemization free.Thus, the opioid peptide, β-casomorphin (Tyr-Pro-Phe-Pro-Gly) and the laminin fragment, Tyr-Ile-Gly-Ser-Arg-NH2 have been obtained in good yields as well as purity.

Silicon tetrachloride-sodium iodide as a deblocking agent for t-butoxycarbonyl group in solid phase peptide synthesis

Deprotection of t-butoxycarbonyl group during solid phase synthesis of peptides can be conveniently and efficiently carried out using a nonhydrolytic and neutral reagent, silicon tetrachloride-sodium iodide (iodotrichlorosilane).The method is simple and r