Aminomethylpiperazines as selective urotensin antagonists
Aminomethylpiperazines, reported previously as being κ-opioid receptor agonists, were identified as lead compounds in the development of selective urotensin receptor antagonists. Optimized substitution of the piperazine moiety has provided high affinity u
Hilfiker, Mark A.,Zhang, Daohua,Dowdell, Sarah E.,Goodman, Krista B.,McAtee, John J.,Dodson, Jason W.,Viet, Andrew Q.,Wang, Gren Z.,Sehon, Clark A.,Behm, David J.,Wu, Zining,Carballo, Luz H.,Douglas, Stephen A.,Neeb, Michael J.
scheme or table
p. 4470 - 4473
(2009/04/06)
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