SYNTHESIS OF 1'-(3-DIMETHYLAMINOPROPYL)-2'-SUBSTITUTED SPIRO.
Reactivity of the C=N bond in spiro has been analysed.Indolines were obtained in practically quantitative yield using organomagnesium reagents in the presence of copper(I) chloride in toluene at 120 deg C.On the basis of an an
Rodriguez, Jose-Gonzalo,Temprano, Fernando
p. 3243 - 3248
(2007/10/02)
2'-Substituted 1'-(2-Dimethylcarbamoylethyl)-3'-spirocycloalkanoindolines: Synthesis and Conformational Analysis of the Propanamide Fragment
2'-Substituted 1'-(2-dimethylcarbamoylethyl)-3'-spirocycloalkanoindolines (2a-f) have been obtained by a phase-transfer attack of 3-chloro-NN-dimethylpropanamide on the indolines (1a-f). 1H N.m.r. spectra of the nitrogen side chain in compounds (2a-f) sho
Benito, Yolanda,Canoira, Laureano,Rodriguez, J. Gonzalo,Temprano, Fernando
p. 423 - 426
(2007/10/02)
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