Synthesis and Antitumor Activity of Analogues of Ifosfamide Modified in the N-(2-Chloroethyl) Group
A series of 3-(2-chloroethyl)-N-(2-X-ethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxides with various X substituents have been prepared by cyclization of racemic ifosfamide or its enantiomers with sodium hydride and subsequent treatment of intermed
Misiura, Konrad,Kinas, Ryszard W.,Stec, Wojciech J.,Kusnierczyk, Halina,Radzikowski, Czeslaw,Sonoda, Akio
p. 226 - 230
(2007/10/02)
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