111001-48-0 Usage
Type of Compound
Polycyclic aromatic hydrocarbon (PAH)
Potent mutagen
It can cause changes in the DNA sequence, leading to mutations.
Carcinogenic
It has the potential to cause cancer in living organisms.
Formation
Result of the reaction between a benzo(c)phenanthrene diol and an epoxide group.
Presence
Commonly found in cigarette smoke and other sources of combustion.
DNA damage
Can cause damage to the DNA structure, potentially leading to mutations.
Cell transformation
Can induce changes in cell behavior, potentially contributing to the development of cancer.
Implicated in lung cancer
Associated with an increased risk of developing lung cancer.
Respiratory diseases
Linked to the development of other respiratory diseases due to its presence in combustion sources.
Risk Reduction
Minimizing exposure to 1,2-epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrobenzo(c)phenanthrene can help reduce the risk of adverse health effects, including cancer and respiratory diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 111001-48-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,0,0 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 111001-48:
(8*1)+(7*1)+(6*1)+(5*0)+(4*0)+(3*1)+(2*4)+(1*8)=40
40 % 10 = 0
So 111001-48-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H14O3/c19-15-12-8-7-10-6-5-9-3-1-2-4-11(9)13(10)14(12)17-18(21-17)16(15)20/h1-8,15-20H
111001-48-0Relevant articles and documents
An Efficient Synthesis of the Highly Tumorigenic anti-Diol Epoxide Derivative of Benzophenanthrene
Pataki, John,Raddo, Pasquale Di,Harvey, Ronald G.
, p. 840 - 844 (2007/10/02)
Synthesis of the potent tumorigen trans-3,4-dihydroxy-anti-1,2,3,4-tetrahydrobenzophenanthrene (1) in relatively few steps and superior overall yield is described.The method entails synthesis of the key intermediate 3-hydroxybenzophenanthrene (7b) v
