111042-91-2

Basic information

• Product Name: Thieno[2,3-c]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI)
• Synonyms: Thieno[2,3-c]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI);3-Amino-thieno[2,3-c]pyridine-2-carboxylic acid methyl ester
• CAS NO: 111042-91-2
• Molecular Formula: C9H8N2O2S
• Molecular Weight: 208.23702
• Product Categories: AMINOACID
• Mol File: 111042-91-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Thieno[2,3-c]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-c]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI)(111042-91-2)
• EPA Substance Registry System: Thieno[2,3-c]pyridine-2-carboxylic acid, 3-amino-, methyl ester (9CI)(111042-91-2)

Safety Data

• Hazardous Substances Data: 111042-91-2(Hazardous Substances Data)

Upstream product

• 68325-15-5 3-chloro-isonicotinonitrile 
• 2365-48-2 Methyl thioglycolate 
• 100-48-1 pyridine-4-carbonitrile 

Relevant articles and documents

INHIBITORS OF THE KYNURENINE PATHWAY

The present application provides novel inhibitors of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase, metabolites thereof, and phannaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. A therapeutically effective amount of one or more of the compounds of formula (I) is useful in treating diseases resulting from dysregulation of the kynurenine pathway. Compounds of formula (I) act by inhibiting the enzymatic activity or expression of indoleamine 2,3-dioxygenase-1 and/or indoleamine 2,3-dioxygenase-2 and/or tryptophan 2,3-dioxygenase.

Nucleophilic Displacements in Pyridine Rings

The reactions of halopyridines containing an electron withdrawing group (-CN, -CO2R, -COMe, -NO2) with sulphur nucleophiles is reported.