111049-33-3

Basic information

• Product Name: 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide
• Synonyms: 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide
• CAS NO: 111049-33-3
• Molecular Formula: C17H25 Cl N4 O3
• Molecular Weight: 368.86
• Mol File: 111049-33-3.mol

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.26g/cm³
• Refractive Index: 1.577
• CAS DataBase Reference: 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide(111049-33-3)
• EPA Substance Registry System: 5-Chloro-N-(2-(diethylamino)ethyl)-4-((4,5-dihydro-2-oxazolyl)amino)-2 -methoxybenzamide(111049-33-3)

Safety Data

• Hazardous Substances Data: 111049-33-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H25ClN4O3/c1-4-22(5-2)8-6-19-16(23)12-10-13(18)14(11-15(12)24-3)21-17-20-7-9-25-17/h10-11H,4-9H2,1-3H3,(H,19,23)(H,20,21)

Relevant articles and documents

Method of providing anxiolytic and antipsychotic treatment with substituted benzamides

The present invention relates to the application of substituted benzamides of formula (I): STR1 in which: A is diethylaminoethyl, 1-ethyl-2-pyrrolidinylmethyl or 1-allyl-2-pyrrolidinylmethyl; R1 is hydrogen or methyl; X is chlorine or bromine; Z is --NH-- or --O-- except when Z is --NH--, R1 is hydrogen and X is chlorine, and of their pharmacologically acceptable addition salts, as anxiolytics and antipsychotics.

Method of treating disorders of cognitive function with substituted benzamides

The invention relates to the use of benzamide derivatives of the formula: STR1 in which: A is a diethylaminoethyl group or a group of the formula II: STR2 where R is a C1 -C3 alkyl, allyl, cyclopropylmethyl or cyclohexenylmethyl group, X is a chlorine or bromine atom, and Z is --NH-- or --O-- with the following condition: when Z is --O--, A is a diethylaminoethyl group, and their pharmacologically acceptable salts for the preparation of medicinal products which are useful in the treatment and prevention of disorders of the cognitive function.

Method of increasing gastrointestinal motility with substituted benzamides

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Novel benzamides, intermediates and process for the preparation and therapeutic use thereof

New substituted benzamides have the general formula: STR1 A=alkyl, alkenyl, diethylaminoethyl or STR2 R1, R2 =H, C1 -C6 alkyl, C2 -C6 alkenyl; R3, R4, R5, R6 =hydrogen or C1 -C6 alkyl; X=halogen; Y=H, halogen; Z=NH, oxygen or sulfur; their optical isomers and their physiologically acceptable salts. The compounds are used as activators of the central nervous system.