COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
The invention provides a novel class of compounds of formula 1, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.
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Page/Page column 37
(2011/04/14)
PYRAZOLE COMPOUNDS
The present invention is directed to compounds of Formula (I) and to pharmaceutically acceptable salts thereof, their synthesis, and their use as Raf inhibitors.
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Page/Page column 40; 59
(2009/03/07)
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