111742-46-2Relevant articles and documents
A NEW SYNTHETIC ENTRY INTO THE TRICYCLO3,7>OCTANE SKELETON
Camps, P.,Iglesias, C.,Lozano, R.,Miranda, M. A.,Rodriguez, M. J.
, p. 1831 - 1832 (1987)
A short synthesis of dimethyl tricyclo3,7>octane-1,5-dicarboxylate, 13, and its 3,7-dimethyl-derivative, 14, by iodine oxidation of the bis-enolate derived from the corresponding dimethyl cis-bicyclooctane-3,7-dicarboxylate, 11 or 12, is described.
Design, synthesis and evaluation of synthetic receptors for the recognition of aspartate pairs in an α-helical confirmation
Albert, Jeffrey S.,Peczuh, Mark W.,Hamilton, Andrew D.
, p. 1455 - 1467 (2007/10/03)
The specific targeting of protein surface functional groups remains a largely unexplored aspect in molecular recognition. In this study, a series of zwitterionic, 16-mer peptides serve as models for the recognition of carboxylate pairs in proteins. A rece
A Short Synthesis of Dimethyl Tricyclo3,7>octane-1,5-dicarboxylate and its 3,7-Dimethyl Derivative. A New Route to the Tricyclo3,7>octane Skeleton
Camps, Pelayo,Iglesias, Carmen,Rodriguez, Maria Jesus,Grancha, Maria Desamparados,Gregori, Maria Eugenia,et al.
, p. 647 - 654 (2007/10/02)
Five-step syntheses of dimethyl tricyclo3,7>octane-1,5-dicarboxylate (13) and its 3,7-dimethyl derivative 14 from the readily available cis-bicyclooctane-3,7-diones 1 and 2, respectively, are described.The key-step implies the iodine oxidation of the bis-enolate derived from the corresponding dimethyl cis-bicyclooctane-3,7-dicarboxylates 11 and 12, thus being developed a new synthetic entry into the tricyclo3,7>octane skeleton.Also, some attempts to synthesize diester 13 by using known methodology for the synthesis of compounds containing this tricyclic skeleton are described.
