- ATF6 MODULATORS AND USES THEREOF
-
Compounds (I) as modulators of Activating Transcription Factor 6 (ATF6) are provided. The compounds may find use as therapeutic agents for the treatment of diseases or disorders mediated by ATF6 and may find particular use in the treatment of viral infections, neurodegenerative diseases, vascular diseases, or cancer.
- -
-
Paragraph 201
(2021/04/17)
-
- VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS
-
FGFR and VEGFR inhibitors are provided, and compounds represented by formula (1) or formula (II) as FGFR and VEGFR inhibitors, pharmaceutically acceptable salts or tautomers thereof are specifically disclosed.
- -
-
Paragraph 0576; 0577
(2018/06/23)
-
- CYCLIC COMPOUND
-
The present invention provides compounds having a Toll-like receptor 4 (TLR4) signaling inhibitory action useful as preventive and therapeutic drugs of autoimmune disease and/or inflammatory disease or diseases such as chemotherapy-induced peripheral neuropathy (CIPN), chemotherapy-induced neuropathic pain (CINP), liver injury, ischemia-reperfusion injury (IRI) and the like. The present invention relates to a compound represented by formula (I) and a salt thereof: (wherein, each symbol is explained in greater detail in the specification).
- -
-
Paragraph 0349
(2018/04/13)
-
- Herbicidal triazolinones
-
A herbicidal compound which is a Q-substituted 1-aryl-4,5-dihydro-1,2,4-triazol-5(1H)-one in which the Q-substituent is on the ring-carbon atom at the 5-position of the aryl group and in which: Q is (a) --CH(R1)ZR in which Z is O or S(O)n and n is zero, one or two; or (b) --CH(R1)N(R4)(R5); or (c) --C(R9)=NR6 ; or STR1
- -
-
-
- Herbicidal aryl tetrahydrophthalimides
-
A herbicidal compound of the formula STR1 where X is F, Cl or Br, Y is Cl, Br, CHF2 O or CF3, R is alkyl of 1 to 6 carbon atoms or lower halo alkyl and R' is H or lower alkyl. Related compounds, including those which have --SR or --NR2 R in place of --OR are also disclosed.
- -
-
-