112489-40-4

Basic information

• Product Name: 9H-Xanthene, 2,7-dibromo-9-chloro-9-phenyl-
• CAS NO: 112489-40-4
• Molecular Formula: C19H11Br2ClO
• Molecular Weight: 450.557
• Mol File: 112489-40-4.mol

Chemical Properties

• CAS DataBase Reference: 9H-Xanthene, 2,7-dibromo-9-chloro-9-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-Xanthene, 2,7-dibromo-9-chloro-9-phenyl-(112489-40-4)
• EPA Substance Registry System: 9H-Xanthene, 2,7-dibromo-9-chloro-9-phenyl-(112489-40-4)

Safety Data

• Hazardous Substances Data: 112489-40-4(Hazardous Substances Data)

Upstream product

• 40102-85-0 2,7-dibromo-9H-xanthen-9-one 
• 90-47-1 xanth-9-one 
• 136345-30-7 2,7-dibromo-9-phenylxanthene-9-ol 

Downstream Products

• 112489-41-5 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-D-myo-inositol 
• 112489-41-5 rac. 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 
• 112489-43-7 rac. hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-myo-inositol 1,4,5-triphosphate 
• 112489-43-7 hexakis(2-cyanoethyl) 2,3-O-cyclopentylidine-6-O-(2,7-dibromo-9-phenylxanthen-9-yl)-D-myo-inositol 1,4,5-triphosphate 
• 112489-44-8 C₃₀H₃₁Br₂O₁₆P₃ 
• 112489-44-8 C₃₀H₃₁Br₂O₁₆P₃ 
• 136345-28-3 2,7-Dibromo-9-ethoxy-9-phenylxanthene 
• 136345-32-9 5'-O-(2,7-Dibromo-9-phenylxanthen-9-yl)thymidine 

Relevant articles and documents

SYNTHESIS OF D-myo-INOSYTOL 1,4,5-TRIPHOSPHATE

The conversion of myo-inositol into the ammonium salts both of racemic and enantiomerically pure D-myo-inositol 1,4,5-triphosphate (6) is described.The n.m.r. spectroscopic properties and biological activity of synthetic and naturally-isolated (6) are virtually identical.

Some Substituted 9-Phenylxanthen-9-yl Protecting Groups

Xanthen-9-one 8 was converted into 9-(4-methoxyphenyl)-, 9-(4-methylphenyl)- and 9--xanthen-9-ol (10; R1 = OMe, R2 = H, 10; R1 = Me, R2 = H, and 10; R1 = H, R2 = CF3, respectively).The corresponding 5'-protected thymidine derivatives (13; R1 = OMe, R2 = H, 13; R1 = Me, R2 = H and 13; R1 = H, R2 = CF3) were obtained in satisfactory yields from thymidine 12 and the appropriate 9-chloro compounds (11; R1 = OMe, R2 = H, 11; R1 = Me, R2 = H and 11; R1 = H, R2 = CF3).In the same way, 2,7-dibromoxanthen-9-one 14 was converted into two 9-aryl-2,7-dibromoxanthen-9-ols ( compounds 15a and 15b).Reaction between thymidine 12 and the corresponding 9-chlorocompounds gave the 5'-protected thymidine derivatives 16a and 16b, also in satisfactory yields.The rates of acid-catalysed cleavage of the above five 5'-protected thymidine derivatives (13; R1 = OMe, R2 = H, 13; R1 = Me, R2 = H and 13; R1 = H, R2 = CF3), 16a and 16b were compared with those of 5'-O-(9-phenylxanthen-9-yl)thymidine 13; R1 = R2 = H and 5'-O-(triphenylmethyl)thymidine 3a; B = thymin-1-yl under the same conditions.