Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties
A series of bromophenol derivatives were synthesized and evaluated as protein tyrosine phosphatase 1B (PTP1B) inhibitors in vitro and in vivo based on bromophenol 4e (IC50 = 2.42 μmol/L), which was isolated from red algae Rhodomela confervoides
Shi, Dayong,Li, Jing,Jiang, Bo,Guo, Shuju,Su, Hua,Wang, Tao
p. 2827 - 2832
(2012/06/01)
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