cas 113082-39-6, 2-chloro-6-Methylquinazoline | Articles data ｜lookchem

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113082-39-6

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AMINOISOXAZOLINE COMPOUNDS AS AGONISTS OF ALPHA7-NICOTINIC ACETYLCHOLINE RECEPTORS
The present invention relates to novel aminoisoxazoline compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of α7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
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Paragraph 00426; 00427

(2017/05/19)

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Chemical Properties

Boiling Point: 269.8±23.0 °C(Predicted)
Density: 1.292
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
PKA: 0.36±0.30(Predicted)
PSA: 25.78000
LogP: 2.59160

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