A new construction of diversely functionalized oxazoles from enolizable cyclic 1,3-dicarbonyls and 5(4H)-oxazolones
A new method for the synthesis of diversely functionalized oxazoles has been developed. The transformation consists of an acylation of enolizable cyclic 1,3-dicarbonyls by 5(4H)-oxazolones followed by rapid cyclization promoted by trifluoroacetic anhydrid