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2,3-Dihydro-1H-indole-5-sulfonic acid methylamide, a sulfonamide derivative of indole with the molecular formula C9H10N2O2S, is a chemical compound that is widely used in various industries. It is known for its potential applications in pharmaceuticals, chemical research, and the synthesis of dyes and pigments.

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  • 113162-46-2 Structure
  • Basic information

    1. Product Name: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE
    2. Synonyms: BUTTPARK 120\07-99;2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE
    3. CAS NO:113162-46-2
    4. Molecular Formula: C9H12N2O2S
    5. Molecular Weight: 212.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 113162-46-2.mol
  • Chemical Properties

    1. Melting Point: 123-124 °C
    2. Boiling Point: 395.8±52.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.285±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 12.54±0.20(Predicted)
    10. CAS DataBase Reference: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(113162-46-2)
    12. EPA Substance Registry System: 2,3-DIHYDRO-1H-INDOLE-5-SULFONIC ACID METHYLAMIDE(113162-46-2)
  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 113162-46-2(Hazardous Substances Data)

113162-46-2 Usage

Uses

Used in Pharmaceutical Industry:
2,3-Dihydro-1H-indole-5-sulfonic acid methylamide is used as a key intermediate in the synthesis of potential drug candidates. Its unique chemical structure allows for the development of new therapeutic agents with potential applications in various medical fields.
Used in Chemical Research:
In the realm of chemical research, 2,3-Dihydro-1H-indole-5-sulfonic acid methylamide serves as a valuable compound for the development of new materials. Its properties and reactivity contribute to the advancement of chemical science and technology.
Used in Dye and Pigment Synthesis:
2,3-Dihydro-1H-indole-5-sulfonic acid methylamide is used as an intermediate in the production of dyes and pigments. Its chemical properties make it a suitable component for the creation of a wide range of colorants used in various industries, such as textiles, plastics, and printing.
Used in Biological Research:
2,3-Dihydro-1H-indole-5-sulfonic acid methylamide has been studied for its potential biological activities, such as anti-inflammatory and anti-cancer properties. Its presence in biological research indicates the possibility of developing new therapeutic strategies based on its unique characteristics.

Check Digit Verification of cas no

The CAS Registry Mumber 113162-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,3,1,6 and 2 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 113162-46:
(8*1)+(7*1)+(6*3)+(5*1)+(4*6)+(3*2)+(2*4)+(1*6)=82
82 % 10 = 2
So 113162-46-2 is a valid CAS Registry Number.

113162-46-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name N-methyl-2,3-dihydro-1H-indole-5-sulfonamide

1.2 Other means of identification

Product number -
Other names N-methyl-indoline-5-sulfonamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:113162-46-2 SDS

113162-46-2Downstream Products

113162-46-2Relevant articles and documents

Diarylsulfonylureas for use in treating secretory diarrhea

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, (2008/06/13)

This invention provides methods of treating secretory diarrhea or cystic fibrosis in a mammal which comprises administering to a mammal in need thereof an effective amount of diarylsulfonylurea. This invention also describes specific diarylsulfonylureas f

Antitumor compositions and methods of treatment

-

, (2008/06/13)

This invention provides certain sulfonamidoquinoxaline derivatives and methods for using them in the treatment of susceptible neoplasms in mammals. Also provided are certain novel pharmaceutical formulations employing these sulfonamidoquinoxaline derivatives, in combination with a carrier, diluent or excipient.

Indole-sulfonamides as antitumor agents

-

, (2008/06/13)

This invention provides certain indolinesulfonamide and substituted-indolesulfonamide derivatives of the formula wherein: R1 is C1-C6 alkyl;, R2 and R3 are independently selected from the group consisting of hydrogen, halo, C1-C6 alkyl, and trifluoromethyl, provided that no more than one of R2 and R3 can be hydrogen;, and methods for using them in the treatment of susceptible neoplasms in mammals. Also provided are certain novel pharmaceutical formulations employing these indolinesulfonamide and substituted-indolesulfonamide derivatives in combination with a carrier, excipient or diluent, as well as processes for preparing the compounds.

Antitumor compositions and methods of treatment

-

, (2008/06/13)

This invention provides the use of certain tetra-substituted imidazolidin-2-one derivatives in the treatment of susceptible neoplasms in mammals. Also provided are certain novel tetra-substituted imidazolidin-2-one derivatives and pharmaceutical formulati

Regioselectivity of Electrophilic Aromatic Substitution: Syntheses of 6- and 7-Sulfamoylindolines and -indoles

Borror, Alan L.,Chinoporos, Efthimios,Filosa, Michael P.,Herchen, Stephen R.,Petersen, Cheryl Pizzo,Stern, Carol A.

, p. 2047 - 2052 (2007/10/02)

The previously reported chlorosulfonation of 1-acetyl-5-bromoindoline at the 7-position is in error.In actuality, the 6-substituted product is the sole regioisomer produced.This regiochemical assignment is based on NMR data and confirmed by X-ray analysis.We have prepared the first 7-sulfamoylindoline and the corresponding indole from indoline using the indoline nitrogen to direct sulfamoylation intarmolecularly to the 7-position.The new 7-substituted derivatives may prove to be important as intermediates to indole-based dyes and as herbicides.

Color transfer photographic processes and products with indole phthalein filter dyes

-

, (2008/06/13)

This invention relates to diffusion transfer photographic processes adapted to be performed in the presence of ambient light and to diffusion transfer products useful in such processes wherein enhanced opacification particularly, in the green region of the visible spectrum is achieved by employing a 7-sulfonamido/5- or 6-sulfamoyl indole phthalein as the light-absorbing, pH-sensitive optical filter agent for the shorter wavelength region of the visible spectrum.

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