cas 1131992-30-7, 6-BROMO-2,4-DICHLORO-7H-PYRROLO[2,3-D]PYRIMIDINE | Articles data ｜lookchem

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1131992-30-7

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KRAS G12C Mutant protein inhibitors
The invention discloses compounds which irreversibly inhibit KRAS G12C mutation. A pharmaceutically acceptable salt and of the compound contains the compound or a salt thereof, and the invention also discloses an application of the compound or a salt and of the compound in the treatment KRAS G12C of a proliferative disease such as a sudden tumor.
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(2021/11/26)

PYRROLOPYRIMIDINE COMPOUNDS
Compounds of formula (I) are A2B receptor antagonists: wherein Ri is optionally substituted aryl or an optionally substituted monocyclic heteroaryl group having 5 or 6 ring atoms; R2 and R3 are independently selected from
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Page/Page column 33-34; 15

(2009/04/25)

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1131992-34-1
6-bromo-2,4-dichloro-7-methylpyrrolo[2,3-d]pyrimidine

Chemical Properties

Density: 2.078±0.06 g/cm3(Predicted)
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
PKA: 8.62±0.50(Predicted)
PSA: 41.57000
LogP: 3.02720

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