PHENYLENE, FURYL, AND THIENYL LEUKOTRIENE B4 ANALOGUES
This invention relates to leukotriene B 4 antagonists having the structure STR1 and the pharmaceutically acceptable addition salts thereof; wherein R 1 is lower alkyl having 1-10 carbon atoms; or lower alkenyl or alkynyl having 2-10 carbon atoms; or lower
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(2008/06/13)
The Synthesis of Aromatic Leukotriene Analogues; Regioselective Trapping of 2,4'-Dilithiophenylethyne
The 8,11-bridged aromatic leukotriene B4 analogues (3), (4), and (5), in which conformational freedom is restricted, have been prepared by extremely short synthetic routes.Conditions are described which allow the regioselective electrophillic t
Furber, Mark,Taylor, Richard J. K.,Burford, S. Cliff
p. 1573 - 1578
(2007/10/02)
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