Cu/HP20-catalyzed solvent-free huisgen cycloaddition at ordinary temperatures
We have developed an environmentally friendly and highly efficient solvent-free Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction using a polymer-supported copper catalyst (Cu/HP20). Substrates poorly soluble in common organic solvents are also
Copper/HP20: Novel and polymer-supported copper catalyst for huisgen cycloaddition
A polymer-supported copper catalyst (Cu/HP20) is easily prepared in water and effectively catalyzed the Huisgen cycloaddition between azides and terminal alkynes.